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		<title>Skye Bioscience, Inc. News Releases</title>
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		<description>Latest news from Skye Bioscience, Inc., as distributed by TMX Newsfile.</description>
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			<title>Skye Bioscience to Participate in Upcoming Investment Conferences</title>
			<link>https://www.newsfilecorp.com/release/275680/Skye-Bioscience-to-Participate-in-Upcoming-Investment-Conferences</link>
			<description>San Diego, California--(Newsfile Corp. - November 24, 2025) - Skye Bioscience, Inc. (NASDAQ: SKYE) ("Skye"), a clinical-stage biotechnology company focused on unlocking new therapeutic pathways for obesity and other metabolic health disorders, will participate in the following upcoming investment conferences:Citi Global Healthcare Conference (Miami)1x1 meetings: Dec. 2Evercore Annual Healthcare Conference (Coral Gables)Fireside Chat: Dec. 3, 12:55 pm ET1x1 meetingsPiper Sandler Annual Healthcare...&lt;img src="https://api.newsfilecorp.com/newsinfo/275680/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Mon, 24 Nov 2025 07:00:00 -0500</pubDate>
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			<title>Skye Bioscience Announces $40 Million Private Placement Equity Financing</title>
			<link>https://www.newsfilecorp.com/release/201199/Skye-Bioscience-Announces-40-Million-Private-Placement-Equity-Financing</link>
			<description>Financing expected to fund strategic expansion of obesity clinical development and extend operating runway beyond 2026 San Diego, California--(Newsfile Corp. - March 11, 2024) - Skye Bioscience, Inc. (OTCQB: SKYE) (the Company), a clinical stage biotechnology company focused on the discovery, development and commercialization of novel classes of therapeutic drugs that modulate the endocannabinoid system, today announced that it has entered into a securities purchase agreement for the sale of...&lt;img src="https://api.newsfilecorp.com/newsinfo/201199/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Mon, 11 Mar 2024 09:20:00 -0400</pubDate>
			<category domain="https://www.newsfilecorp.com/language">en</category>
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			<atom:subtitle>Financing expected to fund strategic expansion of obesity clinical development and extend operating runway beyond 2026</atom:subtitle>
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			<title>Skye Bioscience to Present at Oppenheimer Investor Conference</title>
			<link>https://www.newsfilecorp.com/release/197129/Skye-Bioscience-to-Present-at-Oppenheimer-Investor-Conference</link>
			<description>San Diego, California--(Newsfile Corp. - February 7, 2024) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye"), a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel classes of therapeutic drugs that modulate the endocannabinoid system, today announced that it will present an overview of the company and its programs in obesity and glaucoma at the 34th Annual Oppenheimer Healthcare Life Sciences Conference.Date: February 13 - 14, 2024Location:...&lt;img src="https://api.newsfilecorp.com/newsinfo/197129/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Wed, 07 Feb 2024 07:00:00 -0500</pubDate>
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			<title>Skye Bioscience Announces $50.25 Million Private Placement Equity Financing</title>
			<link>https://www.newsfilecorp.com/release/195997/Skye-Bioscience-Announces-50.25-Million-Private-Placement-Equity-Financing</link>
			<description>Financing co-led by a leading life science investor and 5AM Ventures expected to fully fund obesity Phase 2 trial assessing nimacimab, Skye's differentiated peripheral CB1 inhibitor, in combination with a GLP-1R agonist San Diego, California--(Newsfile Corp. - January 29, 2024) - Skye Bioscience, Inc. (OTCQB: SKYE) ("the Company"), a clinical stage biotechnology company focused on the discovery, development and commercialization of novel classes of therapeutic drugs that modulate the...&lt;img src="https://api.newsfilecorp.com/newsinfo/195997/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Mon, 29 Jan 2024 08:00:00 -0500</pubDate>
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			<atom:subtitle>Financing co-led by a leading life science investor and 5AM Ventures expected to fully fund obesity Phase 2 trial assessing nimacimab, Skye's differentiated peripheral CB1 inhibitor, in combination with a GLP-1R agonist</atom:subtitle>
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			<title>Skye Bioscience Receives IND Clearance for Phase 2 Clinical Trial of Nimacimab in Obesity and Chronic Kidney Disease</title>
			<link>https://www.newsfilecorp.com/release/193647/Skye-Bioscience-Receives-IND-Clearance-for-Phase-2-Clinical-Trial-of-Nimacimab-in-Obesity-and-Chronic-Kidney-Disease</link>
			<description>Phase 2 trial to assess impact of peripherally-acting CB1 inhibitor on weight loss and metabolic biomarkers related to co-morbid obesity and chronic kidney disease San Francisco, California--(Newsfile Corp. - January 9, 2024) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye" or the "Company"), a pharmaceutical company developing drugs targeting the endocannabinoid system, has received clearance of its Investigational New Drug ("IND") application with the U.S. Food and Drug Administration ("FDA") to...&lt;img src="https://api.newsfilecorp.com/newsinfo/193647/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Tue, 09 Jan 2024 07:00:00 -0500</pubDate>
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			<atom:subtitle>Phase 2 trial to assess impact of peripherally-acting CB1 inhibitor on weight loss and metabolic biomarkers related to co-morbid obesity and chronic kidney disease</atom:subtitle>
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			<title>Skye Bioscience Responds to OTC Markets Promotional Policy</title>
			<link>https://www.newsfilecorp.com/release/190434/Skye-Bioscience-Responds-to-OTC-Markets-Promotional-Policy</link>
			<description>San Diego, California--(Newsfile Corp. - December 8, 2023) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye" or the "Company"), a pharmaceutical company developing drugs targeting the endocannabinoid system, focusing on metabolic conditions and glaucoma, has received a request by OTC Markets Group Inc. ("OTC Markets") to issue this statement about promotional activity concerning its common shares traded on the OTCQB market (operated by OTC Markets).On Monday, December 4, 2023, OTC Markets informed...&lt;img src="https://api.newsfilecorp.com/newsinfo/190434/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Fri, 08 Dec 2023 17:14:00 -0500</pubDate>
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			<title>Skye Bioscience and Tautomer Bioscience Enter Exclusive License for SBI-100 for Development and Sale of Products for Chronic Pain and Other Indications in South Africa and Rest of Africa</title>
			<link>https://www.newsfilecorp.com/release/189857/Skye-Bioscience-and-Tautomer-Bioscience-Enter-Exclusive-License-for-SBI100-for-Development-and-Sale-of-Products-for-Chronic-Pain-and-Other-Indications-in-South-Africa-and-Rest-of-Africa</link>
			<description>San Diego, California and Johannesburg, South Africa--(Newsfile Corp. - December 5, 2023) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye"), a pharmaceutical company developing drugs targeting the endocannabinoid system, and Tautomer Bioscience (Pty) Limited ("Tautomer"), a privately-owned biopharmaceutical company focused on addressing unmet medical needs in oncology, pain management and infectious diseases, announced today that they have entered into an agreement under which Skye is providing...&lt;img src="https://api.newsfilecorp.com/newsinfo/189857/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Tue, 05 Dec 2023 07:00:00 -0500</pubDate>
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			<title>Skye Bioscience to Present at BTIG Ophthalmology Day and OIS XIII Ophthalmology Innovation Summit</title>
			<link>https://www.newsfilecorp.com/release/188199/Skye-Bioscience-to-Present-at-BTIG-Ophthalmology-Day-and-OIS-XIII-Ophthalmology-Innovation-Summit</link>
			<description>San Diego, California--(Newsfile Corp. - November 21, 2023) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye"), a pharmaceutical company developing drugs targeting the endocannabinoid system to address diseases including glaucoma and metabolic conditions, will present an overview of its glaucoma program at two ophthalmology-focused conferences. Company executives will introduce SBI-100 Ophthalmic Emulsion, Skye's first-in-class CB1 agonist, highlight recent Phase 1 data, and outline details of its...&lt;img src="https://api.newsfilecorp.com/newsinfo/188199/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Tue, 21 Nov 2023 07:00:00 -0500</pubDate>
			<category domain="https://www.newsfilecorp.com/language">en</category>
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			<title>Skye Bioscience Announces Positive Phase 1 Trial Results for SBI-100 Ophthalmic Emulsion, Its First-in-Class CB1 Agonist Being Developed for the Treatment of Glaucoma</title>
			<link>https://www.newsfilecorp.com/release/185167/Skye-Bioscience-Announces-Positive-Phase-1-Trial-Results-for-SBI100-Ophthalmic-Emulsion-Its-FirstinClass-CB1-Agonist-Being-Developed-for-the-Treatment-of-Glaucoma</link>
			<description>•          SBI-100 OE is well tolerated, with low rate of hyperaemia (8.4%)•          Reduced intraocular pressure (23% mean reduction) in healthy volunteers with higher baseline IOP (&gt;17 mm Hg)San Diego, California--(Newsfile Corp. - October 25, 2023) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye" or the "Company"), a pharmaceutical company developing drugs targeting the endocannabinoid system, initially focused on the CB1 receptor to address glaucoma and metabolic conditions, is pleased to...&lt;img src="https://api.newsfilecorp.com/newsinfo/185167/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Wed, 25 Oct 2023 07:00:00 -0400</pubDate>
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			<title>CORRECTION: Skye Bioscience to Host Virtual Investor Day on October 25, 2023: "CB1 Axis: Unlocking the Pharmaceutical Potential of the Endocannabinoid System"</title>
			<link>https://www.newsfilecorp.com/release/184638/CORRECTION-Skye-Bioscience-to-Host-Virtual-Investor-Day-on-October-25-2023-CB1-Axis-Unlocking-the-Pharmaceutical-Potential-of-the-Endocannabinoid-System</link>
			<description>Phase 1 clinical data to be released in conjunction with Investor Day This document replaces and updates the previous version with the current OTCQB ticker for Skye Bioscience, Inc.San Diego, California--(Newsfile Corp. - October 20, 2023) - Skye Bioscience, Inc. (OTCQB: SKYE) ("Skye" or the "Company"), a pharmaceutical company developing drugs targeting the endocannabinoid system, initially through modulation of the CB1 receptor, to address diseases including glaucoma and metabolic conditions,...&lt;img src="https://api.newsfilecorp.com/newsinfo/184638/156" id="156" width="2" height="2" style="width: 1px;  height: 1px;border: 0px solid;" /&gt;</description>
			<pubDate>Fri, 20 Oct 2023 00:59:00 -0400</pubDate>
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			<atom:subtitle>Phase 1 clinical data to be released in conjunction with Investor Day</atom:subtitle>
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